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Projects. Life and Matter Sciences

Exosomes: intercellular communication as a therapeutic weapon

List of projects selected in the 18th National Programme

Study of EBV, HHV-6A AND HHV-6B MICRO-RNAs in plasma isolated exosomes of patients with multiple sclerosis: correlation with activity and progression of disease
Lead Researcher: Roberto Álvarez Lafuente
Research Centre: Hospital Universitario Clínico San Carlos. Instituto de Investigación Sanitaria San Carlos (IdISSC). Madrid.

Modulation of exosomes transporting miRNAs and lncRNAs for intercellular communication as therapeutic tools in dyslipidemia treatment
Lead Researcher: Alberto Dávalos Herrera
Research Centre: Instituto Madrileño de Estudios Avanzados (IMDEA) en Alimentación. Madrid.

Characterization of infection biomarkers and possible drug targets present into exosome vesicles generated during in vitro and in vivo infection by Leishmania infantum.
Lead Researcher: Vicente Larraga Rodríguez de Vera
Research Centre: Centro de Investigaciones Biológicas. CSIC. Madrid.

Applicability of exosomes as predictors of response to treatment and prognosis in breast cancer: cellular modifications induced by the interaction of exovesicles
Lead Researcher: Fernando Rodríguez Serrano
Research Centre:Instituto de Biopatología y Medicina Regenerativa. Centro de Investigación Biomédica. Universidad de Granada.

Molecular mechanisms involved in the production of exosomes in cell stress
Lead Researcher: Antonio Zorzano Olarte
Research Centre: Instituto de Investigación Biomédica (IRB) Barcelona.

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